0 Comments
Les Quatre Souhais Saint Martin, Audigier, andīeranger au Long Cul ( Beranger of the Long Ass).Ī bookseller's term for obscene or humorous books.įA ËRIE: Tolkien contrasted the fairy (the mythic creature) with Faërie, the latter being both the Otherworld realm where elves and fey creatures held sway and more generally the sense of magic and wonder associated with that place. Including the stories of the Shipman, the Friar, the Miller, Included several fabliaux in The Canterbury Tales, Mishaps, scatology, mistaken identity, and bodily humor. Tales frequently revolve around trickery, practical jokes, sexual Traditionally wrote the story in octosyllabic couplets. Or "dirty" narrative popular with French poets, who Handout discussing the difference between fables andįABLIAU(plural, fabliaux): A humorous, frequently ribald Afterġ600s, fables increasingly became common as a form of children's A famous collectionīidpai (circa 300 CE), and in the medieval period, Marieĭe France (c. Works to produce the tales we know today. Greek writer Aesop is most credited as an author ofįables, but Phaedrus and Babrius in the first century (CE) The reader learns the lesson as an exemplum-an example Each animal is not necessarily a symbol for something However, unlike a parable, the lesson learned is not necessarilyĪllegorical. I.e., a person can learn practical lessons from the fictional Objects reveals general truths about human nature, Unlike the parables, fables often include talking animalsĬharacters. Vocabulary terms are listed alphabetically.Ī brief story illustrating human tendencies through animal characters. Important concepts and vocabulary that we will cover during
Whether you prefer to to maintain the natural tone of the wood, or use a darker stain or oil, or apply lacquer for a more highly polished appearance, is completely up to you. It is slightly denser than silver maple with a Janka rating of 850 lbf. Growing in the coastal regions of the Pacific northwest, it is virtually the only commercially harvested maple species in the region. But, of course, the texture and intensity of natural wood coloration are far superior to veneer alternatives.īecause the pigment of maple wood burls is light in color compared to most other wood species, you have many options for finishing your wood pieces. Big leaf maple: Big leaf maple gets its name from its massive leaves, generally between six- and 12-inches wide. Big Leaf Maple is prized for its lightness, resonance and fine grain patterns. These attributes are so valued that an entire industry has been built around producing artificial "look-alike" wood burl veneer. It is a highly desired burl because of its intense eye and figure. This tonewood choice gives a sweet clarity with a full dynamic range. Over 1,000 guitar wood sets and necks individually pictured. Prop 65 / SDS Wood & Dust Supplier Code of Ethics Terms of Sales Terms of Purchase Timber & Lumber Suppliers Contact Us. The figured patterns and bold colors found in the grain of burl wood are unlike any other wood design, which makes them highly-prized for showing off fine craftsmanship. Guitar Wood from Oregon Wild Wood - the largest online selection of luthier tonewoods. Other Common Names: Big Leaf Maple, Oregon Maple, Northwest Maple, Red Maple, Western Maple. In doing this, retaining the naturally rough, unkempt edges of the burl wood in your finished piece of furniture will display eye-catching contours and really show off the uniqueness of the wood. It is the largest maple tree that grows in North America and derives its name from its leaf. While on the high end it will be just one defect from Musical grade.One popular use of burls is to carefully plane, sand and finish them to create a beautifully-textured surface that can be used as a coffee table or other decor item. Bigleaf maple is the only Western species of the soft maples. Quilted figure occurs in the Big Leaf Maple tree of the Pacific Northwest U.S. The tree can produce many different types of figure, including quilted (tubular, popcorn, & cloud), curly (fiddleback, broken, & basketweave), and burl. Youll appreciate how substantially softer it is than Hard Maple, too. It has the distinction of having the largest leaf of the Maples-up to 15' in diameter. On the low end you will get intense deep figure with sporadic but aesthetically pleasing placement on the board. Quilted Big Leaf Maple Acer macrophyllum This tree is native to the Pacific Northwest. Value A term Kimball Hardwoods uses to describe an item for sale that may have some imperfections inside the Template. Mature bigleaf maples grow to about 50 ft tall but can reach 100 ft with. The Bigleaf Maple is one of the few trees viable as a commercial hardwood species in the Pacific northwest. Check out our Maple Tree Auction page - Hundreds of Maples for sale. We are always adding to the maple wood collection so keep checking back for more great wood. This grade may have natural defect such as, burl eye or cluster, bird peck, pin knot. The wood has been used to make piano frames and the tree can be tapped for maple syrup. Our maple burl wood is salvaged from the Pacific Northwest coastal range of Gold Beach, Oregon. Figure can wane in areas and material will be free of end checking.ĪAAAA is a clear grade, free from surface and end checking, splits and cracks. Cherry may have some sap wood, tight knots. There will be areas where there is no figure, tight knots may also appear. AAAA Maple and Myrtlewood will have light figure all over or light to bold figure sporadically all over the board or block. ft.) Hardness 850 Janka Rating -34.11 softer than red oak (1290 psi) Density 0.48 Specific Gravity -25.00 less dense than red oak (.64) General Workability Somewhat Difficult 7/10 Red Oak Wood Texture V. We grade our material once it is dried and surfaced.ĪAAA is our “furniture grade” material. We made up our own grading system, as there are no industry standards for grading figure, materials grade is mainly on intensity figure and then with the clarity and grain of the board. We have 3 grades, AAAA (4A), AAAAAA (5A), and Musical. L-Citrulline: BUCKED UP® contains 6 grams of L-Citrulline. The primary driving mechanism being the link between hordenine and the protection and release of norepinephrine, which in turn stimulates your central nervous system leading to countless benefits.* An underground metabolism and mental booster not just touted in body building communities, but has seen an increase in popularity in gaming and silicon valley for: increased attention span, calorie burning, mood, and productivity. Hordenine: A plant based compound that has been shown to have a: nootropic increase, physical performance increase, but a fat burning increase as well. Huperzine A has also been shown to promote healthy hormone levels, increase memory retention, promote mitochondria and liver health, and even prevent neuron death from toxicity.* Not only does it prevent acetylcholine breakdown, but has been shown to increase levels for up to 6 hours post consumption. Huperzine A: A plant based alkaloid extract that has been shown to prevent the breakdown of acetylcholine, a key component of brain function. Other ingredients: natural and artificial flavors, citric acid, sucralose, malic acid,silicone dioxide, calcium silicate, malic acid, yellow 5 lake Sodium (as Himalayan Rock Salt with trace minerals) There’s only one thing that matters here - your goals. What is the Black Editition Difference?īlack Edition adds the a special mineral blend of Humic & Fulvic acid to help detoxify the system and promote healthy nutrient absorption. Listen up BAMF, it’s time to meet your demands. Why that’s important: Any elite performance is an outcome of your brain melding with its synapses so they’re firing synergistically, commanding your body - muscles and all - to achieve the performance you demand of it - and yourself. Hordenine for next-level focus, AlphaSize to help elevate mental sharpness, and Huperzine-A to accelerate memory recall. Teaming up with all the other adept ingredients, BAMF helps upgrade your brain’s CPU, closes every window and stops every process except for the one that matters: YOUR WORKOUT.īAMF also strengthens your mind-muscle connection. Using three nootropics shown to positive impacts on cognitive function and motivation, BAMF is both your brain’s geek squad and task manager. The perfect pump and focus pre workout!Įver had those days where your brain feels like a computer that’s running on dial-up, has seven windows up, music streaming, solitaire in the background, and the fan’s broken? You slog into the gym still thinking about assignments, deadlines, and if you’ll be forever alone. Trying to close everything else down so you can fire on all cylinders and conquer your workout is futile. BAMF High Stimulant Pre Workout This is the strongest overall pre-workout from overall ingredients. NASA’s Goddard Space Flight Center, Greenbelt, Maryland procures and manages the SEWP V effort. These Government-Wide Acquisition Contracts are available for ordering by all NASA centers, all federal agencies and their contractors. The principal purpose of the SEWP V contracts is to provide state-of-the-art information technology and computer technologies, high-end scientific and engineering processing capabilities, network equipment and peripherals. 31, 2019, and one five-year option to extend the period of performance through Oct. The minimum amount of supplies or services that may be ordered is $25.00 with a maximum of $20 billion per contract.Įach contract will have an effective ordering period of 10 years, consisting of a five-year base period from Nov. Twenty-three contracts were awarded in the Computer Based Systems, Group A, and 33 contracts were awarded in the Networking/Security/Video and Conference Tools, Group D.Īll the awards are for firm-fixed-price, indefinite-delivery/indefinite-quantity contracts. 52.NASA has awarded 56 contracts under the Solutions for Enterprise-Wide Procurement (SEWP) V. Do you have suggestions about new technology, services, or processes you would like to see included in SEWP VI that will benefit the Federal Government If so.52.232-33 Payment by Electronic Funds Transfer-System for Award Management (OCT 2018).52.222-50 Combating Trafficking in Persons (JAN 2019).52.222-41 Service Contract Labor Standards (AUG 2018).52.222-19 Child Labor - Cooperation with Authorities and Remedies (OCT 2019).
With great monitoring and recording quality and a flexible I/O configuration, the SSL 2+ comes highly recommended. A +48v option also allows the connection of both condenser and dynamic mics. There are two combi mic/line inputs with Hi-Z (impedance) options for switching between guitar and bass signals or those from synths or drum machines. There's also the 4k button which adds some extra presence and high-end zing (and, more importantly, makes you feel that little bit more 'pro'). This is the big brother to the standard SSL2, the main difference being that the 2+ adds two outputs to the 2-in, 2-out configuration of the 2, MIDI In/Out plus an additional independent headphone out (with both being able to monitor different mixes). Read the full Audient EVO 4 review Best for monitoringĪ compact interface with pro features and connectivity, the SSL2+ promises an affordable version of ‘the SSL sound’, bringing the feel of a gazillion recordings made in 7-figure recording studios within reach of everybody. These are great value too, and the simplest and cleverest solutions we’ve come across. The one-dial solution is beautifully implemented and designed to help make both the EVO 4 and 8 clever, compact desktop solutions that sound great. EVO 8 allows two people to monitor with studio headphones. Using the headphone socket means the main dial controls this level. These are 1 and 2 (for the input levels), and output (bottom right) plus a final button that means the dial adjusts the mix between the input and DAW. Two speaker-outs complete the connections.Ī central main dial controls the level of the output, plus a number of other levels determined largely by which buttons on the top of the panel you press. The more expensive EVO 8 doubles the inputs to four. You’ll find two combi mic/line inputs around the back of the EVO 4, and one instrument level input at the front for connecting guitar or bass (which then overrides the first input around the back). The compact Evo range was launched a couple of years ago to much acclaim. It’s an incredibly fleshed-out and powerful recording experience using one of these and combined with the portable size, it’s the perfect interface for taking to and from recording sessions, with the connectivity to grow with you should you choose to invest further in the UA ecosystem. The front face of the Apollo Twin X features a huge knob that can be used for volume control of monitors, headphones, and input gain, as well as some handy buttons for phantom power, muting, and various other features. This means you can load in a vintage Neve channel strip which will modify the behavior of the analog input for some uncanny recreations of proper recording studio channels. This isn’t too different from any other desktop-based interface here, however, the clever bit is how the Unison preamps are matched with DSP processing. There are two hybrid XLR/jack inputs on the back with an instrument input on the front that overrides one of the back connections. It comes in two formats, Duo and Quad which are named for the amount of DSP processing chips they possess. In a welcome move that brings it in line with UAD rack mount interfaces, the Universal Audio Apollo Twin X has some incredibly powerful features that will offer a serious upgrade to anyone’s home recording experience. Looking for good deals on audio interfaces? We're updating our Prime Day music deals page round the clock for all the best products and biggest savings on Amazon and beyond. Whatever your interfacing needs, there should be something here for you. Then we look in detail at each of the interfaces on our full list, including full reviews if you want to know more. We have options covering everything from multi-input options to great entry-level interfaces. First we reveal our top recommendations with some of the best audio interfaces you can buy right now. If you’d like to learn more we recommend you start there.īut if you just want to read about the best audio interfaces out there right away, keep scrolling. We’ve also included some expert buying advice and information about how we test audio interfaces. There are many audio interfaces available on the market, so how do you choose which is the best one for you and your studio? We'll tell you everything you need to know, what you need and why you need it towards the end of this buyer’s guide. You’ll also be able to record singing or speech via a microphone connected to one of the interface’s inputs. Once you’ve decided on the right audio interface, you can then easily record gear like electric and acoustic guitars, synths and any other musical equipment straight into a DAW of your choice. Finally, there are limited validation data of microarray results by a gold-standard technique (bisulfite-PCR). The sensitivity of antibody-based methods is undetermined and possibly low (in our experience). Methods that rely on frequent sites (HpaII/MspI) result in a high genome fraction to amplify (high complexity), which limits PCR efficiency and ends up favoring non-CpG island DNA. There are major problems with each published method. 2004) or antibodies that recognize 5-methyl cytidine ( Weber et al. Most of the published methods aim at selective enrichment for the methylated fraction of the genome, using either methylation-sensitive restriction enzymes ( Yan et al. Several platforms are available, with variation in genome representation and probe size (oligonucleotides, short DNA fragments, or BACs).Ī major issue in methylation microarrays is the protocol for target preparation. Microarray chips containing promoter sequences filled this gap. Although efficient, both methods lack the high throughput required to study large sample collections for clinical and/or epidemiological purposes. 2000) and also revealed the existence of coordinated hypermethylation of multiple genes in subsets of samples, a process termed CpG island methylator phenotype ( Toyota et al. The use of techniques that test DNA methylation in an unbiased way, such as MCA (methylated CpG island amplification) and RLGS (restriction landmark genomic scanning), revealed that DNA methylation in cancer happens in a tissue-specific pattern ( Costello et al. Much of the knowledge about aberrant DNA methylation in cancer came from genome-wide investigations. While normal patterns of DNA methylation are important for genomic imprinting, X-chromosome inactivation, and to repress mobilization of repetitive elements, aberrant DNA methylation in cancer is associated with silencing of tumor-suppressor genes and genes involved in invasion, angiogenesis, and apoptosis ( Sugimura and Ushijima 2000 Toyota and Issa 2005). This happens by the enzymatic addition of methyl groups to CpG dinucleotides in an orchestrated reaction that involves DNA methyltransferases, methyl-binding domain proteins, and histone deacetylases ( Herman and Baylin 2003 Laird 2005). One of the main causes of epigenetic silencing in cancer is DNA methylation of cytosines in CG-rich regions (CpG islands) close to gene promoters. In cancer, loss of expression of selected genes happens by either genetic mutation or epigenetic silencing. In summary, MCAM is a suitable technique to discover methylated genes and to profile methylation changes in clinical samples in a high-throughput fashion. Unsupervised hierarchical clustering segregated the tumors into the expected subgroups based on CpG island methylator phenotype classification. The sensitivity and specificity of the method to detect hypermethylated loci were 88% and 96%, respectively, according to validation by bisulfite-PCR. We validated this method in three cancer cell lines and 15 primary colorectal tumors, resulting in the discovery of hundreds of new methylated genes in cancer. Here we overcome this limitation and present an improved method to identify methylated genes genome-wide by hybridizing a CpG island microarray with amplicons obtained by the methylated CpG island amplification technique (MCAM). The lack of high-throughput methods with high specificity and sensitivity to detect changes in DNA methylation has limited its application for clinical profiling. An abnormal pattern of DNA methylation occurs at specific genes in almost all neoplasms. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |